Association Between HTLV-1 Infection and Nasopharyngeal Carcinoma: A Case-Control Study

  • Sare Hosseini Cancer Research Center, Mashhad University of Medical Sciences
  • Mahmoudreza Kalantari
  • Shakiba Kalantari
  • Mohammad Reza Majidi
  • Houshang Rafatpanah Baygi
  • Seyed Alireza Javadinia
Keywords: HTLV-1 Nasopharyngeal Carcinoma Polymerase Chain Reaction

Abstract

Background:

The northeast of Iran is one of the endemic regions of human T-cell lymphotropic virus type-1 (HTLV-1). This study aimed to evaluate the relationship between nasopharyngeal carcinoma and HTLV-1 infection in northeast Iran, an endemic area for HTLV-1.

Methods:

In this case-control study, paraffin-embedded nasopharyngeal tissue samples of patients with definitive nasopharyngeal carcinoma were evaluated for the presence of the HTLV-1 genome by polymerase chain reaction retrospectively.

Results:

Thirty patients with nasopharyngeal carcinoma and 30 healthy people were evaluated. All participants were matched in terms of age and gender, and all were living in Mashhad. The HTLV-1 genome was detected in only one of the people in the healthy group.

Conclusions:

The HTLV-1 infection and nasopharyngeal carcinoma did not correlate significantly.

Published
2023-03-06
How to Cite
Hosseini, S., Kalantari, M., Kalantari, S., Majidi, M. R., Rafatpanah Baygi, H., & Javadinia, S. A. (2023). Association Between HTLV-1 Infection and Nasopharyngeal Carcinoma: A Case-Control Study. Reports of Radiotherapy and Oncology, 8(1), 1-3. Retrieved from http://waocp.com/journal/index.php/Reports-of-Radiotherapy-and-Onco/article/view/2282
Issue
Vol 8 No 1 (2021)
Section
Articles