Therapeutic Potential of Curcumin in Breast Cancer: From Basic Research to Clinical Applications

  • Amir Avan Metabolic syndrome Research center, Mashhad University of Medical Sciences
  • Milad Hashemzehi
  • Soodabeh ShahidSales
  • Seyed Mahdi Hassanian
  • Mona Joudi Mashhad
  • Majid Khazaei
Keywords: Curcumin Breast Cancer Anticancer Effects

Abstract

Breast cancer is among the most common types of cancer and the second leading cause of cancer-related death in women. Therefore, finding treatments with the highest effectiveness and least side effects is of great importance. Curcuma langa, commonly known as curcumin, has many advantages, including antioxidant, antiinflammatory, anticancer, and wound-healing properties. The anticancer mechanisms include prevention of malignant cell formation, as well as reduction of angiogenesis and tumor growth, as documented in some malignancies, including pancreatic, ovarian, gastric, and colorectal cancers. Recent research has also documented curcumin activities against breast cancer, in particular molecular pathways involved in cell growth, differentiation, apoptosis, and suppression of inflammation. Therefore, the aim of the current review was to study the effects of curcumin on breast cancer.

Conflicts of Interest:

The authors declare no conflicts of interest.

Published
2015-12-31
How to Cite
Avan, A., Hashemzehi, M., ShahidSales, S., Hassanian, S. M., Joudi Mashhad, M., & Khazaei, M. (2015). Therapeutic Potential of Curcumin in Breast Cancer: From Basic Research to Clinical Applications. Reports of Radiotherapy and Oncology, 2(4), 1-6. Retrieved from http://waocp.com/journal/index.php/Reports-of-Radiotherapy-and-Onco/article/view/2361
Issue
Vol 2 No 4 (2015)
Section
Articles