Clinical and Histopathological Features of Adenomatoid Tumor; A Case Report and Review of the Literature

Abstract

Background: Adenomatoid tumor is a rare benign neoplasm of mesothelial origin that can occur in both genital and extragenital sites. Diagnosis is often challenging because of its broad histopathological spectrum. Accurate diagnosis is essential to avoid misdiagnosis and unnecessary radical surgical procedures.

Case Presentation: A 53-year-old man presented with a five-month history of mild right testicular pain. Clinical and radiological evaluation revealed a firm, well-circumscribed 2-cm mass arising from the tail of the epididymis, with normal serum tumor markers and unremarkable staging investigations. The lesion was surgically excised. Gross examination demonstrated a solid yellowish-black cut surface. Histopathological examination revealed a well-circumscribed benign neoplasm composed of vacuolated cuboidal cells arranged in nests and trabeculae within a fibrous stroma, without nuclear atypia, mitotic activity, or necrosis. The findings were consistent with an epididymal adenomatoid tumor.

Conclusion: Adenomatoid tumor of the epididymis is a rare benign mesothelial neoplasm that requires careful clinicopathological evaluation to ensure accurate diagnosis and to avoid unnecessary radical surgery.