The Role of Chloroform Exposure and Risk of Leukemia: A Protocol of Systematic Review and Meta-Analysis

2024-01-23T07:48:38+00:00

Background: Leukemia is a serious health problem and the possibility of its association with chloroform raises the question of environmental risk. This systematic review aims to provide a comprehensive review of the available evidence on the association between chloroform and leukemia.
Methods: Qualitative research using qualitative methods in primary literature. Studies were selected and data extracted, followed by qualitative analysis. Meta-analysis, subgroup analysis, sensitivity analysis, dose-response analysis, heterogeneity study, integration of GRADE assessment, forest plots, published results, assessment of the prevalence of injustice, and fairness judgments are systematically addressed.
Results: The study selection process outlined inclusion and exclusion criteria. Descriptive analysis describes the key characteristics of the included studies, while quantitative analysis presents the results of the meta-analysis. A sensitivity analysis assessed the quality of the results and examined publication bias due to poor reporting.
Conclusion: This systematic review summarizes the current evidence on chloroform exposure and leukemia risk and provides public information for future research and health interventions.

Wood Dust and Risk of Leukemia: A Protocol of Systematic Review and Meta-Analysis

2024-01-23T07:51:04+00:00

Background: Leukemia is a type of cancer caused by the growth of blood cells, especially in the bones and blood. Although extensive research has investigated various environmental factors that increase the risk of leukemia, the relationship between dust exposure and leukemia remains a topic of interest. Wood dusting is a common activity in industries such as carpentry and woodworking, and its potential link to leukemia warrants a comprehensive review to evaluate the available evidence. Understanding this organization is important for occupational health and safety advice and will assist in prevention strategies for those at risk.
Methods: We conducted a systematic review and analysis of the existing literature on the relationship between wood dust and leukemia. A comprehensive search of electronic databases, including PubMed, Scopus, and Web of Science, was conducted to identify relevant studies up to the date of review. Methods included peer-reviewed literature, cohort studies, case-control studies, and meta-analyses of peer-reviewed studies such as chip injury and leukemia. Priority will be given to studies with clear evaluation criteria and strong analytical ability.
Results: The review identified a total of [X] studies that met the inclusion criteria. These studies reveal different groups of people and workplaces with different levels of wood dust. The extracted data showed various associations between wood dust and leukemia, including positive, negative or neutral effects. Meta-analyses were conducted to provide a synthesis of the available evidence. Subgroup analysis was based on characteristics such as study design, population characteristics, and dust levels. A sensitivity analysis was performed to evaluate the effectiveness of all outcomes. Potential sources of heterogeneity between studies were explored and the quality of evidence was assessed by design.

Asian Pacific Journal of Environment and Cancer

The Role of Chloroform Exposure and Risk of Leukemia: A Protocol of Systematic Review and Meta-Analysis

Wood Dust and Risk of Leukemia: A Protocol of Systematic Review and Meta-Analysis