Aptamers and Cancer

Authors

  • Nasrin Yazdanpanahi Department of Biochemistry, The Islamic Azad University, Flaverjan Brach, Isfahan, Iran.
  • Mehrdad Hashemi Department of Molecular Genetics, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran. 3Department of Medical Genetics, Cancer Research Center, Shohada Hospital, School of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
  • Abolfazl Movafagh

DOI:

https://doi.org/10.31557/apjcb.2016.1.1.3-7

Keywords:

Aptamer- canter- SELEX technique

Abstract

Oligonucleotides Aptamers are single strands of DNA and RNA with the length of 20-100 nucleotides or peptides and unique three dimensional structure that is affected by nucleotide sequence. The structure exclusively influences aptamers’ bindings with its target molecule. It reduces performance or inactivate protein and this feature is used for therapeutic purposes. In addition and through connecting to signature molecule, aptamers are used to detect specific proteins. High efficiency of aptamer technology makes them a valuable tool for diagnosing and treating different diseases including cancer. The present study is an attempt to review recent studies in this field.

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Published

2016-04-25

How to Cite

1.
Yazdanpanahi N, Hashemi M, Movafagh A. Aptamers and Cancer. Asian Pac J Cancer Biol [Internet]. 2016 Apr. 25 [cited 2026 Jun. 4];1(1):3. Available from: http://waocp.com/journal/index.php/apjcb/article/view/189

Issue

Vol. 1 No. 1 (2016)

Section

Research Articles/ Original Work

License

 West Asia Organization for Cabcer Prevention retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License 4 (This permits anyone to copy, distribute, transmit and adapt the published work, provided the original work and source are appropriately cited).