Squamous Cell Carcinoma Bartholin’s Gland: Management Challenges: Case Report and Review of Literature

Authors

  • Pallavi Verma Associate Professor, Obstetrics and Gynecology (Gynaecologic Oncology), INHS Asvini Mumbai, India.
  • Sushil Chawla Professor and Head of department, Obstetrics and Gynaecology, INHS Asvini Mumbai, India.
  • Sandhyarani - Postgraduate Resident, Obstetrics and Gynecology, INHS Asvini Mumbai, India.
  • Sunil Anand Associate Professor, Reconstructive surgery, INHS Asvini Mumbai, India.
  • Rahul Mahajan Assistant Professor, Obstetrics & Gynaecology, INHS Asvini Mumbai, India.
  • Divya Shelly Professor, Pathology, INHS Asvini Mumbai, India.

Keywords:

Bartholin’s gland carcinoma, Squamous cell carcinoma, Human Papilloma Virus

Abstract

Bartholin gland carcinoma is an unusual malignancy, accounting for less than 5% of all vulval cancers. Squamous cell carcinoma is the most common histological type, followed by adenocarcinoma. Bartholin’s gland carcinomas develop into masses of varying sizes and may be ulcerated or deep to the surface with the overlying skin intact. Because little is known about bartholin’s gland cancer, it is frequently misdiagnosed as an abscess or a cyst. Diagnosis is often delayed until discovered at advanced stages. To add to the literature, we report a case of locally advanced stage bartholin’s gland carcinoma in a postmenopausal lady, who is managed with radical partial vulvectomy with bilateral inguinofemoral lymphadenectomy with vulvar-vaginal reconstruction by gracilis myocutaneous flap followed by adjuvant concurrent chemoradiation. We aim to create awareness among clinicians and provide new insights for the diagnosis and treatment of this rare malignancy.

Published

2025-04-16

Issue

Section

Case report