Investigation of Low-Level Laser Radiation Effects on Blood Smears Haematological Indices in Breast Carcinoma Patients: Interpretation of Cellular Answers and Clinical Manifestations
DOI:
https://doi.org/10.31557/apjcb.2026.11.1.93-101Keywords:
: LLLT, hemoglobin, WBC, breast cancer, immunityAbstract
Background: Low-level laser therapy (LLLT) is able to modulate cellular and immune reactions in clinical conditions.
Objective: The purpose of the present investigation was to evaluate the effect of LLLT on blood smear hematological parameters in patients with breast carcinoma.
Methods: Red blood cell (RBC) count, white blood cell (WBC) count, hemoglobin content, and platelet count were measured in control and in laser-irradiated samples for different exposure times.”
Results: Time-dependent increase in RBC number and hemoglobin was observed, peaking at 1 minute of exposure. WBC and platelet numbers were insignificantly altered. Morphological examination, on the other hand, revealed the increased percentage of reactive lymphocytes, indicating immune cell activation.
Conclusion: The results suggest that LLLT influences cellular shape but not leukocyte numbers to a great extent, suggesting potential immunomodulatory effects that warrant further investigation in vivo.
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West Asia Organization for Cabcer Prevention retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License 4 (This permits anyone to copy, distribute, transmit and adapt the published work, provided the original work and source are appropriately cited).





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